Episode 1Guest co-host Fred Willard; actress Jennifer Beals; boxer Randy Couture; Jonny Lang performs.
Episode 2
E2
Episode 2Guest co-host Fred Willard; TV personality Keshia Knight Pulliam ("Celebrity Mole Yucatan"); comic Tony Camin.
Episode 3
E3
Episode 3Guest co-host Fred Willard; actor Hank Azaria; NASCAR driver Michael Waltrip; competitive eater Sonya Thomas.
Episode 4
E4
Episode 4Guest co-host Fred Willard; journalist John Stossel; former NFL player Lawrence Taylor; Coheed and Cambria perform.
Episode 5
E5
Episode 5Guest co-host Fred Willard; musician Nick Lachey; pro football player Warren Sapp; Shelby Lynne performs; Jimmy Kimmel broadcasts from a Houston family's home in anticipation of the Super Bowl.
Episode 6
E6
Episode 6Guest co-host Kathie Lee Gifford; actress Leah Remini; actor Will Arnett; comic Don Barris.
Episode 7
E7
Episode 7Guest co-host Kathie Lee Gifford; comic Adam Carolla ("The Man Show"); actress Susie Essman; comic Craig Robinson.
Episode 8
E8
Episode 8Guest co-host Kathie Lee Gifford; singer Kylie Minogue; actor Adam Rodriguez; the Black Eyed Peas perform.
Episode 9
E9
Episode 9Guest co-host Kathie Lee Gifford; former pro basketball player Magic Johnson; singer Missy Elliott; Buddy Guy performs.
Episode 10
E10
Episode 10Guest co-host Kathie Lee Gifford; TV host Pat O'Brien; Kenny Chesney performs.
Episode 11
E11
Episode 11Guest co-host Warren Sapp; comic Jim Florentine; Olympic softball pitcher Jennie Finch; the Fab Four perform.
Episode 12
E12
Episode 12Guest co-host Warren Sapp; actor Dean Cain; the Bug Brothers Tim and Derek Majewski; Dizzee Rascal performs.
Episode 179
E179
Episode 179Actor Billy Bob Thornton; actor Dominic Monaghan; pitcher Pedro Martinez's lucky charm, Nelson de la Rosa.
Episode 180
E180
Episode 180Model Brooke Burke; Tears for Fears performs.
Episode 181
E181
Episode 181Actor/comic Patton Oswalt; Bowling for Soup performs.
Episode 186
E186
Episode 186Actor Blair Underwood; actress Virginia Madsen; Interpol performs.
Episode 191
E191
Episode 191Actor Adam Brody; TV personality Ben Stein.
Episode 208
E208
Episode 208Actor Robin Williams; Guerilla Black performs.
